圖書名稱

Computational Non-coding RNA Biology

內(nèi)容簡介：

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules.

Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis.

計算非編碼 RNA 生物學是計算非編碼 RNA 的資源。本書涵蓋了非編碼 RNA 的鑒定和定量計算方法，包括 miRNA、tasiRNA、phasiRNA、lariat 起源的 circRNA 和反剪接 circRNA、miRNA/siRNA 靶標的鑒定以及 miRNA 中突變和編輯位點的鑒定。本書介紹了計算方法的基本思想及其詳細的計算步驟，這是開發(fā)高通量測序技術的關鍵組成部分，用于識別不同類別的非編碼 RNA 并預測這些分子的可能功能。從高通量測序數(shù)據(jù)集中查找、定量和可視化非編碼 RNA 非常復雜。因此，生物學家通常可以完成所有必要的分析步驟。